Chinese Journal Of Cell And Stem Cell >Archive >2020 >Volume 10 Number 3 June 2020 >Reviews >contents

Journal content

Research progress of the regulating mechanisms of microglia on neural stem cells

Wang Zening, Hou Boru, Jiang Cheng, et al


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【Abstract】 Brain injury is closely related to neuro inflammation and microglia is one of the key factors in the brain injury. Microglia could obtain the pro-inflammation or anti-inflammation charaters, but how could them affects neural stem cells (NSCs) was still controversial. Microglia can polarize into M1 type microglia and M2 type microglia under different conditions, which have different effects on the regulation of neural stem cells. The mechanism has not yet been elucidated, this article reviews the regulation mechanisms of different types of microglia on neural stem cells.
 

【Key words】 Microglia; Regulatory mechanism; Neural stem cells